Effects on the cardiovascular system
Puerarin can play an effective antihypertensive role in hypertensive animals. Puerarin can promote the local microvascular blood flow and movement of the amplitude increase, resulting in accelerated circulation velocity, promote the normal brain microcirculation of the human body, reduce microcirculation obstacles. In addition, puerarin can also play a good role in improving the nail wrinkle microcirculation of patients with sudden deafness. Puerarin can clear blood vessel congestion, speed up blood flow, so as to eventually restore the hearing of patients. Puerarin can help treat arrhythmias. Puerarin contains beta-blockers, which fight premature heart beats and ventricular tachycardia, reducing the incidence of arrhythmias. Puerarin can reduce tachycardia and play a good role in treating arrhythmia in clinic. Puerarin can protect ischemic myocardium, increase the blood flow of ischemic myocardium and increase collateral blood flow to treat ischemic myocardium.
Application:
Puerarin clinical application range is wide, not only to angina, coronary heart disease, myocardial infarction and cardiovascular system diseases such as hypertension have clinical value, for diseases of the cardiovascular system, through the use of puerarin can activate blood vessels, improve cardiovascular situation, reduce the risk of cardiovascular disease. In addition, the application of puerarin can also play a certain clinical treatment effect on retinal arteriovenous obstruction, optic nerve atrophy, sudden deafness and other diseases.
Puerarin has been recognized by most people for its wide pharmacological activity, clear efficacy and small toxic and side effects. However, puerarin's poor lipid solubility and water solubility and low bioavailability also limit its application. However, in recent years, thanks to the application of some high biocompatibility polymer materials, a variety of puerarin nano preparations have been developed, such as liposomes, nanocrystalline/granule, polymer micelles, microemulsions, dendrimers, etc., which make puerarin evenly dispersed and easier to penetrate through the biofilm. Compared with traditional fast - release tablets, skeleton tablets, solid dispersions and other slow - release preparations, the solubility, stability and bioavailability are increased. With the continuous development of pharmacology theory and the continuous progress of modern medical technology, the study of puerarin is also more in-depth, puerarin will have a broader prospect in the future.
