Tranexamic acid (TXA) is a medication used to treat or prevent excessive blood loss from trauma, surgery, and in various medical conditions including hemophilia and heavy menstrual bleeding. It comes in oral and intravenous forms.
Side effects are uncommon and include gastrointestinal effects, dizziness, fatigue, headache, and hypersensitivity reactions. The medication needs to be used cautiously in people with kidney disease and who are at high risk for blood clots. Tranexamic is safe to use in pregnant women. However, caution should be used in lactating women. It is an antifibrinolytic.
Product Name: Tranexamic Acid
Other Name: trans-4-(Aminomethyl)cyclohexane carboxylic acid
Appearance: White powder
CAS No: 1197-18-8
Molecular Formula: C8H15NO2
Molecular Weight: 157.21
Tranexamic acid exerts its antifibrinolytic effect through the reversible blockade of lysine-binding sites on plasminogen molecules. Tranexamic acid inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.
Tranexamic acid is used as first-line nonhormonal treatment of dysfunctional uterine bleeding, and heavy bleeding associated with uterine fibroids. The histological appearance of the necrosis in women treated by tranexamic acid is no different from the spontaneous incidence of thrombosis.
Tranexamic acid is used in orthopedic surgery to reduce blood loss. Tranexamic acid is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. Tranexamic acid is commonly used in joint replacement surgery.
Tranexamic acid should be considered for use in bleeding trauma patients.
1. In cosmetics.
It can be used in whitening and anti-freckle products, such as water, gel, essence, emulsion, skin care cream and so on. It is suggested to use PH 5.0-60.which will have a better effect in whitening and anti-freckle.
2. In pharmaceuticals:
Tranexamic acid is frequently used following major trauma. Tranexamic acid is used to prevent and treat blood loss in a variety of situations, such as dental procedures for hemophiliacs, heavy menstrual bleeding, and surgeries with high risk of blood loss.
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