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Exemestane,Aromasin, Exemesta,6-Methyleneandrosta-1,4-diene-3,17-dione

Exemestane,Aromasin, Exemesta,6-Methyleneandrosta-1,4-diene-3,17-dione

Prodcut Name:Exemestane
Synonyms: Exemestane,Aromasin, Exemesta,6-Methyleneandrosta-1,4-diene-3,17-dione
CAS NO.: 107868-30-4
Specification: USP
Apperance:White Crystalline Power
Molecular Formula: C20H24O2
Molecular Weight: 296.4034
Melting Point: 155.13℃

Description

WELLGREEN has over ten years manufacturing experience for Exemestane,Aromasin, Exemesta, Exemesta,6-Methyleneandrosta-1,4-diene-3,17-dione for  breast cancer, for radiation in post-menopausal women,for women health care products in China, it is able to supply you  top quality Exemestane,Aromasin, Exemesta, 6-Methyleneandrosta-1,4-diene-3,17-dione with competitive price.

Exemestane,Aromasin, Exemesta,6-Methyleneandrosta-1,4-diene-3,17-dione

Product Description

Exemestane (trade name Aromasin) is a drug used to treat breast cancer. It is a member of the class of drugs known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive,hormonally-responsive, hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers.


Prodcut Name:Exemesta

Synonyms: Exemestane,Aromasin, Exemesta,6-Methyleneandrosta-1,4-diene-3,17-dione

CAS  NO.: 107868-30-4

Specification: USP

Apperance:White Crystalline Power

Molecular Formula: C20H24O2

Molecular Weight: 296.4034

Melting Point: 155.13℃

  

Specification: USP

Item

Spec.

Characteristics

White Crystalline Power

Identification

A: IR

B: RT(HPLC)

Residue on Ignition

≤0.1%

Heavy Metals

≤10ppm

Water

≤0.5%

Specific Optical Rotation

+290~+300°

Impurity


Spirooxiran 1

≤0.15%

Spirooxiran 2

≤0.15%

Exemestane related

Compound C

≤0.15%

Exemestane related

Compound A

≤0.15%

Any unspecified impurity

≤0.10%

Total impurity

≤0.50%

Assay (HPLC)

98.0%~102.0%

Conclusion

USP Pending Monograph, Conform the stipulation

 

Application 

1. Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.


2. It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition."


3. By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen


Packing &Delivery

Delivery time :

Around 3-5 workdays after your payment.

MOQ :

1 kg

Packing :

1 kg with double plastic container inside/Aluminum foil bag outside. 25kg with double plastic container inside/Fiber drum outside.

Payment terms:

T/T or Western Union or Paypal

Srorage :

Stored in dry and cool place, keep away from strong light and heat.

Shelf Life :

Two years when properly stored.

Company Information

Wellgreen Technology Co.,Ltd is a high - tech corporation and ISO9001: 2008 quality management system certification specializing in the production of nutritional supplements, herbal essence, steroids and its intermediates pharmaceutical industry. We insist the principle of  Top quality, Excellent service, Outstanding technology innovation, Constantly development and the goal of To be well in the green life.

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Certifications

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FAQ
Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q3:What’s your MOQ?
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q4: How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q5:Is there a discount?
A:Different quantity has different discount.
Q6: How to contact us ?
A:You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us
.



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  • Wellgreen Technology Co.,Ltd

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    Tel: +86-29-88453375 / 89388326  
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